Cancer-miRNA Regulatory Network

Compendium of miRNA Target Genes

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GLB Brain Sun Cluster Number 27 (172 genes) This page contains all miRNA mediated regulation and functional enrichment for GLB Brain Sun cluster number 27. Information about brain cancer can be found on Wikipedia, and further information about the "GLB Brain Sun" dataset can be found in Sun et al., 2006. Inferred miRNA Mediated Regulation Weeder-miRvestigator PITA TargetScan zzz999 hsa-mir-590-3p hsa-mir-889 Gene Ontology Enrichment GO ID GO Term Annotated Genes in Cluster GO:0000375 RNA splicing, via transesterification reactions 10 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 10 GO:0000398 nuclear mRNA splicing, via spliceosome 10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 82 GO:0006259 DNA metabolic process 18 GO:0006260 DNA replication 11 GO:0006350 transcription, DNA-dependent 55 GO:0006351 transcription, DNA-dependent 43 GO:0006353 transcription termination, DNA-dependent 7 GO:0006396 RNA processing 23 GO:0006397 mRNA processing 19 GO:0008152 metabolic process 110 GO:0008380 RNA splicing 17 GO:0009058 biosynthetic process 73 GO:0009059 macromolecule biosynthetic process 69 GO:0009889 regulation of biosynthetic process 50 GO:0010467 gene expression 76 GO:0010468 regulation of gene expression 49 GO:0010556 regulation of macromolecule biosynthetic process 48 GO:0016070 RNA metabolic process 61 GO:0016071 mRNA metabolic process 21 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 52 GO:0031323 regulation of cellular metabolic process 59 GO:0031326 regulation of cellular biosynthetic process 50 GO:0032774 RNA biosynthetic process 44 GO:0034645 cellular macromolecule biosynthetic process 69 GO:0043170 macromolecule metabolic process 96 GO:0044237 cellular metabolic process 106 GO:0044238 primary metabolic process 107 GO:0044249 cellular biosynthetic process 73 GO:0044260 cellular macromolecule metabolic process 95 GO:0045449 regulation of transcription, DNA-dependent 45 GO:0051095 regulation of helicase activity 3 Overlap Between miRNA Target Genes and Enriched Gene Ontology Annotations miRNA Method GO ID GO Term Overlap GO Annotated Genes Cluster Size miRNA Targets Genes P-Value hsa-mir-889 TargetScan GO:0000375 RNA splicing, via transesterification reactions 4 10 172 53 0.1579151 hsa-mir-590-3p PITA GO:0000375 RNA splicing, via transesterification reactions 3 10 172 31 0.08250583 hsa-mir-889 TargetScan GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 4 10 172 53 0.1579151 hsa-mir-590-3p PITA GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 3 10 172 31 0.08250583 hsa-mir-889 TargetScan GO:0000398 nuclear mRNA splicing, via spliceosome 4 10 172 53 0.1579151 hsa-mir-590-3p PITA GO:0000398 nuclear mRNA splicing, via spliceosome 3 10 172 31 0.08250583 hsa-mir-889 TargetScan GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 18 82 172 53 0.9877499 hsa-mir-590-3p PITA GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 13 82 172 31 0.6934876 hsa-mir-889 TargetScan GO:0006259 DNA metabolic process 4 18 172 53 0.7064484 hsa-mir-590-3p PITA GO:0006259 DNA metabolic process 2 18 172 31 0.6679293 hsa-mir-889 TargetScan GO:0006260 DNA replication 2 11 172 53 0.7157938 hsa-mir-590-3p PITA GO:0006260 DNA replication 1 11 172 31 0.6239183 hsa-mir-889 TargetScan GO:0006350 transcription, DNA-dependent 14 55 172 53 0.8062893 hsa-mir-590-3p PITA GO:0006350 transcription, DNA-dependent 8 55 172 31 0.7221269 hsa-mir-889 TargetScan GO:0006351 transcription, DNA-dependent 12 43 172 53 0.6080315 hsa-mir-590-3p PITA GO:0006351 transcription, DNA-dependent 6 43 172 31 0.7103583 hsa-mir-889 TargetScan GO:0006353 transcription termination, DNA-dependent 2 7 172 53 0.3704143 hsa-mir-590-3p PITA GO:0006353 transcription termination, DNA-dependent 2 7 172 31 0.1115349 hsa-mir-889 TargetScan GO:0006396 RNA processing 4 23 172 53 0.8984189 hsa-mir-590-3p PITA GO:0006396 RNA processing 5 23 172 31 0.2097705 hsa-mir-889 TargetScan GO:0006397 mRNA processing 4 19 172 53 0.7575064 hsa-mir-590-3p PITA GO:0006397 mRNA processing 5 19 172 31 0.09882442 hsa-mir-889 TargetScan GO:0008152 metabolic process 24 110 172 53 0.9993182 hsa-mir-590-3p PITA GO:0008152 metabolic process 16 110 172 31 0.9140137 hsa-mir-889 TargetScan GO:0008380 RNA splicing 4 17 172 53 0.648754 hsa-mir-590-3p PITA GO:0008380 RNA splicing 5 17 172 31 0.05969109 hsa-mir-889 TargetScan GO:0009058 biosynthetic process 17 73 172 53 0.9532484 hsa-mir-590-3p PITA GO:0009058 biosynthetic process 10 73 172 31 0.8571129 hsa-mir-889 TargetScan GO:0009059 macromolecule biosynthetic process 17 69 172 53 0.8980821 hsa-mir-590-3p PITA GO:0009059 macromolecule biosynthetic process 10 69 172 31 0.782148 hsa-mir-889 TargetScan GO:0009889 regulation of biosynthetic process 12 50 172 53 0.8550915 hsa-mir-590-3p PITA GO:0009889 regulation of biosynthetic process 7 50 172 31 0.7414977 hsa-mir-889 TargetScan GO:0010467 gene expression 17 76 172 53 0.9761712 hsa-mir-590-3p PITA GO:0010467 gene expression 14 76 172 31 0.3728023 hsa-mir-889 TargetScan GO:0010468 regulation of gene expression 12 49 172 53 0.8288657 hsa-mir-590-3p PITA GO:0010468 regulation of gene expression 9 49 172 31 0.3775505 hsa-mir-889 TargetScan GO:0010556 regulation of macromolecule biosynthetic process 12 48 172 53 0.7995189 hsa-mir-590-3p PITA GO:0010556 regulation of macromolecule biosynthetic process 7 48 172 31 0.6886846 hsa-mir-889 TargetScan GO:0016070 RNA metabolic process 13 61 172 53 0.9677481 hsa-mir-590-3p PITA GO:0016070 RNA metabolic process 10 61 172 31 0.5760937 hsa-mir-889 TargetScan GO:0016071 mRNA metabolic process 5 21 172 53 0.6804189 hsa-mir-590-3p PITA GO:0016071 mRNA metabolic process 5 21 172 31 0.149265 hsa-mir-889 TargetScan GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 12 52 172 53 0.8985889 hsa-mir-590-3p PITA GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8 52 172 31 0.6405055 hsa-mir-889 TargetScan GO:0031323 regulation of cellular metabolic process 14 59 172 53 0.9007267 hsa-mir-590-3p PITA GO:0031323 regulation of cellular metabolic process 9 59 172 31 0.6778683 hsa-mir-889 TargetScan GO:0031326 regulation of cellular biosynthetic process 12 50 172 53 0.8550915 hsa-mir-590-3p PITA GO:0031326 regulation of cellular biosynthetic process 7 50 172 31 0.7414977 hsa-mir-889 TargetScan GO:0032774 RNA biosynthetic process 12 44 172 53 0.651666 hsa-mir-590-3p PITA GO:0032774 RNA biosynthetic process 6 44 172 31 0.7372601 hsa-mir-889 TargetScan GO:0034645 cellular macromolecule biosynthetic process 17 69 172 53 0.8980821 hsa-mir-590-3p PITA GO:0034645 cellular macromolecule biosynthetic process 10 69 172 31 0.782148 hsa-mir-889 TargetScan GO:0043170 macromolecule metabolic process 22 96 172 53 0.9906741 hsa-mir-590-3p PITA GO:0043170 macromolecule metabolic process 14 96 172 31 0.8683503 hsa-mir-889 TargetScan GO:0044237 cellular metabolic process 23 106 172 53 0.9990055 hsa-mir-590-3p PITA GO:0044237 cellular metabolic process 16 106 172 31 0.8557957 hsa-mir-889 TargetScan GO:0044238 primary metabolic process 23 107 172 53 0.9993201 hsa-mir-590-3p PITA GO:0044238 primary metabolic process 15 107 172 31 0.9379889 hsa-mir-889 TargetScan GO:0044249 cellular biosynthetic process 17 73 172 53 0.9532484 hsa-mir-590-3p PITA GO:0044249 cellular biosynthetic process 10 73 172 31 0.8571129 hsa-mir-889 TargetScan GO:0044260 cellular macromolecule metabolic process 21 95 172 53 0.9950739 hsa-mir-590-3p PITA GO:0044260 cellular macromolecule metabolic process 14 95 172 31 0.8521638 hsa-mir-889 TargetScan GO:0045449 regulation of transcription, DNA-dependent 11 45 172 53 0.8122689 hsa-mir-590-3p PITA GO:0045449 regulation of transcription, DNA-dependent 6 45 172 31 0.7625689 hsa-mir-889 TargetScan GO:0051095 regulation of helicase activity 0 3 172 53 0.6714198 hsa-mir-590-3p PITA GO:0051095 regulation of helicase activity 0 3 172 31 0.4512324

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